| CAS Number | 25013-16-5 |
| Chemical Formula | C₁₁H₁₆O₂ |
| Solubility | insoluble in water; soluble in fats/oils, ethanol, methanol, propylene glycol |
| Storage Conditions | cool, dry, dark storage, protected from light |
| Shelf Life | 24 Months |
Butyl hydroxyanisole (BHA) is a synthetic antioxidant added to foods, cosmetics, and packaging to prevent rancidity and spoilage caused by oxidation.
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Raw Material Charging | Charge the reactor with p-methoxyphenol (hydroquinone monomethyl ether) and an acid catalyst (e.g., phosphoric acid). | Note: Raw materials must meet stringent purity specifications. The catalyst concentration is critical for reaction efficiency and selectivity. |
| 2 | Synthesis (Alkylation) | Introduce isobutylene gas or tert-butanol into the reactor under controlled temperature and pressure. | Control Point: Maintain reactor temperature between 50-80°C. Exothermic reaction requires efficient cooling. Monitor pressure to control the reaction rate and ensure completion. |
| 3 | Neutralization & Washing | Quench the reaction and neutralize the acidic mixture with a caustic solution (e.g., sodium hydroxide). Wash the resulting organic layer with water. | Control Point: Monitor pH closely to ensure complete neutralization of the acid catalyst. Proper washing is essential to remove salts and water-soluble impurities. |
| 4 | Purification (Distillation) | Purify the crude BHA mixture by vacuum distillation to remove unreacted materials and by-products. | Control Point: Precise control over vacuum level and temperature is crucial to separate the two BHA isomers from impurities without causing thermal degradation. |
| 5 | Crystallization | Cool the purified, molten BHA in a crystallizer, possibly with the aid of a suitable solvent, to form solid crystals. | Control Point: The cooling rate profile directly influences crystal size, shape, and purity. Slower cooling generally yields a higher quality product. |
| 6 | Product Isolation | Separate the BHA crystals from the mother liquor using a centrifuge or filter press. | Note: The solid cake may be washed with a cold solvent to remove surface impurities before drying. |
| 7 | Drying | Dry the wet BHA crystals in a vacuum dryer to remove any residual moisture or solvent. | Control Point: Drying temperature must be kept well below the product’s melting point (48-55°C) to prevent clumping. Final moisture content must be below the specified limit (e.g., <0.5%). |
| 8 | Sieving & Blending | Sieve the dried BHA to achieve a uniform particle size and blend different batches if required for homogeneity. | Note: This step ensures the final product has consistent physical properties for customer applications. |
| 9 | Quality Control & Packaging | Test the final product against all specifications (purity, isomer ratio, melting point, heavy metals, etc.). | Control Point: The product must meet all food-grade or pharmaceutical-grade standards. Package in airtight, light-resistant containers to prevent oxidation and degradation. |
Aluminum Foil Bag
lron-ringed Cardboard Drum
25kqs by Drum
25kqs by Drum
Anrui Biotechnology Co., Ltd. is a specialized exporter of high-quality food ingredients and additives. We focus on global trade and custom formulation services for functional ingredients, delivering consistent, compliant, and premium-quality supply solutions to our worldwide clients.
Headquartered in Guangzhou, China, Anrui collaborates with GMP-certified manufacturing partners equipped with advanced testing facilities, including HPLC, UV-VIS spectrophotometry, and microbiological analysis, ensuring every batch meets strict international quality and regulatory standards.
Our products are exported to over 60 countries, serving industries such as food, beverages, supplements, and cosmetics.
Fast-moving ingredients for food factories, ready for immediate dispatch.